Tricarboxylic acids and derivatives
Alkali Scientific Sodium Citrate, Trisodium Salt, Dihydrate, ACS Grade, 500 G
Sodium Citrate, Trisodium Salt, Dihydrate, ACS Grade, is provided in a 500g package for use in laboratory-grade applications, including buffer preparation and biochemical research. Sodium citrate, with its high buffering capacity, plays a crucial role in maintaining stable pH levels during experiments. This ACS-grade product ensures purity and reliability, making it suitable for use in molecular biology, protein chemistry, and clinical diagnostics. It is commonly used in the preparation of buffers, such as those needed for enzyme assays and as an anticoagulant in blood sample preparation. The small package size is ideal for smaller laboratories or those requiring a high-quality reagent for precise experimental conditions.
Selleck Chemical LLC L-Cysteic acid monohydrate S3325-100mg
L-Cysteic acid monohydrate (CAM) is an active endogenous metabolite
Selleck Chemical LLC Pentoxyverine Citrate S4143-100mg
Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold
Medchemexpress LLC Biotin-PEG3-CH2COOH 25mg
Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
Medchemexpress LLC Citrate Synthetase Antibody (YA2802) | 10 UL
Citrate Synthetase Antibody (YA2802) is a rabbit-derived, non-conjugated IgG monoclonal antibody. It targets Citrate Synthetase and is suitable for various antibody-related applications.
- Rabbit-derived
- Non-conjugated IgG monoclonal antibody
- Targets Citrate Synthetase
- Recombinant antibody
- Predicted band size: 52 kDa
- Observed band size: 45 kDa
Medchemexpress LLC Amino-peg3-ch2cooh | 134978-99-7 | 99.9% | C8H17NO5 | 250 MG
Amino-PEG3-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs.
- Functions as a PEG-based PROTAC linker.
- Utilized in the synthesis of PROTACs.
- Has a chemical formula of C8H17NO5.
- Features a molecular weight of 207.22.
- Offers a purity of 99.9%.
- Requires storage at 4°C, protected from light.
- For solutions, store at -80°C for up to 6 months or -20°C for up to 1 month, protected from light.
Medchemexpress LLC Sparfosic acid trisodium | 70962-66-2 | 98.0% | 321.06 | 50 MG
Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase, an enzyme that catalyzes the second step of de novo pyrimidine biosynthesis. It synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines. It is for research use only.
- DNA antimetabolite agent
- Potent inhibitor of aspartate transcarbamoyl transferase
- Synergistically enhances the cytotoxicity of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines
- Causes apoptosis in resistant Br1 cells
- Leads to progressive accumulation of cells in S phase and activation of an apoptotic pathway at 300 μM
- Increases lifespan in mice bearing B16 melanoma
- Curative in 50% of mice with Lewis lung carcinoma when treated on days 1, 5, and 9 following s.c. implantation
Selleck Chemical LLC Toremifene Citrate (NK 622) S1776-1g
Toremifene Citrate (NK 622 NSC 613680) is an oral selective estrogen receptor modulator (SERM) used in the treatment of advanced breast cancer
Medchemexpress LLC MRTX9768 | 2629314-68-5 | 99.48% | 424.43 | 50 MG
MRTX9768 is a potent, selective, orally active, first-in-class PRMT5-MTA complex inhibitor. It inhibits SDMA and cell proliferation in HCT116 MTAP-del cells with marked selectivity over HCT116 MTAP-WT cells. This compound selectively targets MTAP/CDKN2A-deleted tumors, such as glioblastoma, and exhibits a favorable ADME profile.
- Potent and selective PRMT5-MTA complex inhibitor
- Inhibits SDMA and cell proliferation in MTAP-del cells
- Demonstrates dose-dependent inhibition of SDMA in MTAP-del tumors
- Selectively targets MTAP/CDKN2A-deleted tumors, including glioblastoma
- Favorable ADME profile with high bioavailability and moderate to high clearance
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | C15H22O8S | 10MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker with a tosyl cap and a three-unit polyethylene glycol spacer terminating in a carboxylic acid. It is designed for use in the synthesis of PROTACs and other bifunctional molecules where a short, flexible, polar spacer and a carboxyl functional handle are required.
- Tosyl-capped PEG3 spacer ending in a carboxylic acid for conjugation.
- Provides a short, flexible, hydrophilic linker suitable for cellular applications.
- Terminal carboxyl group enables amide or ester coupling chemistries.
- Compatible with solid-phase and solution-phase synthetic workflows.
- Supplied in research-scale quantities for medicinal chemistry and PROTAC development.
- Molecular formula C15H22O8S, molecular weight ≈362.40 g/mol.
Medchemexpress LLC Gefapixant citrate | 2310299-91-1 | 99.2% | 545.52 g/mol | C20H27N5O11S | 5 MG
Gefapixant citrate is the citrate salt of gefapixant, an orally active P2X3 receptor antagonist used in research on chronic cough and pain-related indications. Supplied as a research-grade solid with high purity, it is suitable for in vitro and in vivo studies and is accompanied by technical documentation for analytical use.
- Potent P2X3 receptor antagonist with low-nanomolar activity.
- High purity suitable for research applications.
- Available in small solid quantities for dose-ranging studies.
- Includes datasheet, certificate of analysis, and safety data sheet documentation.
- Soluble stock solutions offered for convenient preparation.
Medchemexpress LLC Diphosphoric acid, mono[(2E)-4-hydroxy-3-methyl-2-butenyl] ester, triammonium salt | 443892-56-6 | 90.0% | C5H21N3O8P2 | 500 UG
HDMAPP triammonium is a potent phosphoantigen in the ammonium and pyrophosphate form of (E)-HDMAPP. It is an activator of γδ T cells and can induce T cell stimulation in vitro with an EC₅₀ of 0.39 nM for TNF-α release.
- Potent phosphoantigen
- Activates γδ T cells
- Induces T cell stimulation in vitro
- Increases TNF-α release in human Vγ9Vδ2 T cells
- Significantly increases γδ cells in cynomolgus monkey model
- White to off-white solid appearance
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.4% | 5 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This compound leverages the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Utilized in antibody-drug conjugate (ADC) synthesis
- Used in PROTAC synthesis
- Leverages intracellular ubiquitin-proteasome system
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 250 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Contains two different ligands connected by a linker
- Suitable for cancer targeted therapy research
Medchemexpress LLC (E/Z)-Zotiraciclib citrate | 1204918-73-9 | C29H32N4O8 | 50 MG
(E/Z)-Zotiraciclib citrate is a potent inhibitor targeting CDK2, JAK2, and FLT3. This compound is supplied as a solid, appearing off-white to light yellow, and is intended for research use only.
- Potent CDK2, JAK2, and FLT3 inhibitor
- High purity: 99.83%
- Molecular weight: 564.59
- Store at 4°C, sealed, away from moisture