Tricarboxylic acids and derivatives
Medchemexpress LLC Tos-peg3-ch2cooh | 1581248-63-6 | 100 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, facilitating its degradation.
- Utilizes the ubiquitin-proteasome system for selective protein degradation.
- Acts as a linker in the construction of degraders.
Electron Microscopy Sciences Ammonium Alcohol 500 ML
Used in Alizarin Red S and Toluidine Blue O for distinction of bone and cartilage in mammalian embryos. See Dawson A.B., Stain Techn., 1:123-4, 1926, Williams, T.W., Stain Techn., 16:23-5, 1941, or Clark, G., (ed), Staining Procedures, 3rd Ed., Williams & Wilkins Baltimore, p. 139, c. 1973
Medchemexpress LLC HY-W016813 100mg Medchemexpress, trans-Aconitic acid CAS:4023-65-8 Purity:>98%
Medchemexpress, HY-W016813 100mg trans-Aconitic acid CAS:4023-65-8 trans-Aconitic acid is present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Amino-PEG5-CH2COOH | 141282-35-1 | ≥97.0% | 500 MG
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Targets PROTAC linkers within the PROTAC pathway
- Solid appearance
- White to off-white color
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 50 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Leverages ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | ≥97.0% | 250 MG
Bromo-PEG1-CH2COOH is a PROTAC linker instrumental in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These PROTACs function by connecting two distinct ligands-one targeting an E3 ubiquitin ligase and the other a protein of interest-thereby exploiting the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Used in the synthesis of PROTACs
- Connects two different ligands
- Designed for selective degradation of target proteins
- Exploits the intracellular ubiquitin-proteasome system
- For research use only
Medchemexpress LLC Subasumstat | 1858276-04-6 | 578.10 | 100 MG
Subasumstat (TAK-981) is a first-in-class and selective inhibitor of the SUMOylation enzymatic cascade, demonstrating potential immune-activating and antineoplastic activities. It increases the production of type 1 IFN, enhancing type 1 IFN-mediated signaling, activating innate effector cells, and improving antitumor innate immune responses. A single subcutaneous injection induces activation of dendritic cells.
- First-in-class selective inhibitor of SUMOylation enzymatic cascade
- Potential immune-activating activities
- Potential antineoplastic activities
- Increases production of type 1 IFN
- Enhances antitumor innate immune responses
- Activates innate effector cells
- Induces activation of dendritic cells
Medchemexpress LLC Dicresulene diammoni 10mg | 10MG
Dicresulene diammonium is an impurity of Policresulen an organic acid with hemostatic antimicrobial and antiviral activities[1 [2
Medchemexpress LLC Boc-NH-PEG2-CH2COOH | 108466-89-3 | 263.29 | 5 G
Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- For research use only
- Molecular formula: C11H21NO6
- Appearance: Liquid, colorless to light yellow
- Storage: Pure form at -20°C for 3 years, 4°C for 2 years
- Storage: In solvent at -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 100 mg/mL
Selleck Chemical LLC Oxacillin sodium monohydrate S2563-50mg
Oxacillin sodium monohydrate (Methicillin) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class
Medchemexpress LLC (E/Z)-Zotiraciclib hydrochloride | 1321626-25-8 | C23H25ClN4O | 5 MG
(E/Z)-Zotiraciclib ((E/Z)-TG02) is an orally active inhibitor of CDK2, JAK2, and FLT3 with IC50s of 13, 73, and 56 nM, respectively. It effectively inhibits the proliferation of cancer cells, making it suitable for cancer research.
- Orally active inhibitor of CDK2, JAK2, and FLT3
- Inhibits proliferation of cancer cells
- Useful for cancer research
- Potently inhibits the CDK2 biomarker pRb